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Mechanism and Therapeutic Targets of c-Jun-N-Terminal Kinases Activation in Nonalcoholic Fatty Liver Disease

Non-alcoholic fatty liver (NAFL) is the most common chronic liver disease. Activation of mitogen-activated kinases (MAPK) cascade, which leads to c-Jun N-terminal kinase (JNK) activation occurs in the liver in response to the nutritional and metabolic stress. The aberrant activation of MAPKs, especi...

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Detalles Bibliográficos
Autores principales: Min, Robert W. M., Aung, Filbert W. M., Liu, Bryant, Arya, Aliza, Win, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406172/
https://www.ncbi.nlm.nih.gov/pubmed/36009582
http://dx.doi.org/10.3390/biomedicines10082035