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Polygenic Risk Score Improves Cataract Prediction in East Asian Population

Cataracts, characterized by crystalline lens opacities in human eyes, is the leading cause of blindness globally. Due to its multifactorial complexity, the molecular mechanisms remain poorly understood. Larger cohorts of genome-wide association studies (GWAS) are needed to investigate cataracts’ gen...

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Detalles Bibliográficos
Autores principales: Hsu, Chih-Chien, Chuang, Hao-Kai, Hsiao, Yu-Jer, Teng, Yuan-Chi, Chiang, Pin-Hsuan, Wang, Yu-Jun, Lin, Ting-Yi, Tsai, Ping-Hsing, Weng, Chang-Chi, Lin, Tai-Chi, Hwang, De-Kuang, Hsieh, Ai-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406175/
https://www.ncbi.nlm.nih.gov/pubmed/36009466
http://dx.doi.org/10.3390/biomedicines10081920