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Multifaceted Roles of the N(6)-Methyladenosine RNA Methyltransferase METTL3 in Cancer and Immune Microenvironment
As the most abundant internal mRNA modification in eukaryotic cells, N(6)-methyladenosine (m(6)A) has emerged as an important regulator of gene expression and has a profound impact on cancer initiation and progression. mRNA m(6)A modification is regulated by m(6)A methyltransferases, demethylases an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406229/ https://www.ncbi.nlm.nih.gov/pubmed/36008936 http://dx.doi.org/10.3390/biom12081042 |