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Multifaceted Roles of the N(6)-Methyladenosine RNA Methyltransferase METTL3 in Cancer and Immune Microenvironment

As the most abundant internal mRNA modification in eukaryotic cells, N(6)-methyladenosine (m(6)A) has emerged as an important regulator of gene expression and has a profound impact on cancer initiation and progression. mRNA m(6)A modification is regulated by m(6)A methyltransferases, demethylases an...

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Detalles Bibliográficos
Autores principales: Hu, Chenxi, Liu, Jiacheng, Li, Yue, Jiang, Wei, Ji, Ding, Liu, Wei, Ma, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406229/
https://www.ncbi.nlm.nih.gov/pubmed/36008936
http://dx.doi.org/10.3390/biom12081042