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Adding Cyclooxygenase Inhibitors to Immune Checkpoint Inhibitors Did Not Improve Outcomes in Metastatic Renal Cell Carcinoma

Modulating the cyclooxygenase 2 (COX-2) pathway has improved responses to immune checkpoint inhibitors (ICIs) in certain solid tumors, such as melanoma. Little is known about COX-2 inhibition in response to ICIs in metastatic renal cell carcinoma (mRCC). In this retrospective cohort study, we examin...

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Detalles Bibliográficos
Autores principales: Zhang, Yumeng, Kumar, Premsai, Adashek, Jacob J., Skelton, William P., Li, Jiannong, Vosoughi, Aram, Chahoud, Jad, Manley, Brandon J., Spiess, Philippe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406439/
https://www.ncbi.nlm.nih.gov/pubmed/36010582
http://dx.doi.org/10.3390/cells11162505