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In Vitro Drug Screening Using iPSC-Derived Cardiomyocytes of a Long QT-Syndrome Patient Carrying KCNQ1 & TRPM4 Dual Mutation: An Experimental Personalized Treatment

Congenital long QT syndrome is a type of inherited cardiovascular disorder characterized by prolonged QT interval. Patient often suffer from syncopal episodes, electrocardiographic abnormalities and life-threatening arrhythmia. Given the complexity of the root cause of the disease, a combination of...

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Detalles Bibliográficos
Autores principales: Wang, Feifei, Han, Yafan, Sang, Wanyue, Wang, Lu, Liang, Xiaoyan, Wang, Liang, Xing, Qiang, Guo, Yankai, Zhang, Jianghua, Zhang, Ling, Zukela, Tuerhong, Xiaokereti, Jiasuoer, Lu, Yanmei, Zhou, Xianhui, Tang, Baopeng, Li, Yaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406448/
https://www.ncbi.nlm.nih.gov/pubmed/36010573
http://dx.doi.org/10.3390/cells11162495