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Padi2/3 Deficiency Alters the Epigenomic Landscape and Causes Premature Differentiation of Mouse Trophoblast Stem Cells

Histone citrullination is a relatively poorly studied epigenetic modification that involves the irreversible conversion of arginine residues into citrulline. It is conferred by a small family of enzymes known as protein arginine deiminases (PADIs). PADI function supports the pluripotent state of emb...

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Detalles Bibliográficos
Autores principales: Ballasy, Noura N., Bering, Elizabeth A., Kokorudz, Caroline, Radford, Bethany N., Zhao, Xiang, Dean, Wendy, Hemberger, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406452/
https://www.ncbi.nlm.nih.gov/pubmed/36010543
http://dx.doi.org/10.3390/cells11162466