Targeting Histone Epigenetic Modifications and DNA Damage Responses in Synthetic Lethality Strategies in Cancer?

SIMPLE SUMMARY: Dynamic chromatin remodeling is regulated by different epigenetic modifications of histones to adapt chromatin to specific cellular functions. Targeting histone epigenetic enzymes will interfere with the correct mechanisms of DNA repair. Therefore, targeting epigenetic enzymes is a p...

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Detalles Bibliográficos
Autor principal: Lazo, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406467/
https://www.ncbi.nlm.nih.gov/pubmed/36011043
http://dx.doi.org/10.3390/cancers14164050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406467/
https://www.ncbi.nlm.nih.gov/pubmed/36011043
http://dx.doi.org/10.3390/cancers14164050

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