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How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer

SIMPLE SUMMARY: This study aims to assess the reliability of using a core-needle biopsy (CNB) for preoperative tumor characterization using gene expression analysis and conventional immunohistochemistry (IHC) analysis for clinical biomarkers in early breast cancer. Obtaining a preoperative CNB is a...

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Detalles Bibliográficos
Autores principales: Saghir, Hani, Veerla, Srinivas, Malmberg, Martin, Rydén, Lisa, Ehinger, Anna, Saal, Lao H., Vallon-Christersson, Johan, Borg, Åke, Hegardt, Cecilia, Larsson, Christer, Haidar, Alaa, Hedenfalk, Ingrid, Loman, Niklas, Kimbung, Siker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406531/
https://www.ncbi.nlm.nih.gov/pubmed/36010992
http://dx.doi.org/10.3390/cancers14164000