Heterogeneity of Cancer-Associated Fibroblasts and the Tumor Immune Microenvironment in Pancreatic Cancer

SIMPLE SUMMARY: Stroma-targeting therapy in pancreatic ductal adenocarcinoma (PDAC) has been extensively investigated, but no candidates have shown efficacy at the clinical trial stage. Studies of cancer-associated fibroblast (CAF) depletion in a mouse model suggested that CAFs have not only tumor-p...

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Detalles Bibliográficos
Autores principales: Shinkawa, Tomohiko, Ohuchida, Kenoki, Nakamura, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406547/
https://www.ncbi.nlm.nih.gov/pubmed/36010986
http://dx.doi.org/10.3390/cancers14163994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406547/
https://www.ncbi.nlm.nih.gov/pubmed/36010986
http://dx.doi.org/10.3390/cancers14163994

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