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Heterogeneity of Cancer-Associated Fibroblasts and the Tumor Immune Microenvironment in Pancreatic Cancer

SIMPLE SUMMARY: Stroma-targeting therapy in pancreatic ductal adenocarcinoma (PDAC) has been extensively investigated, but no candidates have shown efficacy at the clinical trial stage. Studies of cancer-associated fibroblast (CAF) depletion in a mouse model suggested that CAFs have not only tumor-p...

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Detalles Bibliográficos
Autores principales:	Shinkawa, Tomohiko, Ohuchida, Kenoki, Nakamura, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406547/ https://www.ncbi.nlm.nih.gov/pubmed/36010986 http://dx.doi.org/10.3390/cancers14163994

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