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PI3K/AKT/mTOR-Targeted Therapy for Breast Cancer

Phosphatidylinositol 3-kinase (PI3K), protein kinase B (PKB/AKT) and mechanistic target of rapamycin (mTOR) (PAM) pathways play important roles in breast tumorigenesis and confer worse prognosis in breast cancer patients. The inhibitors targeting three key nodes of these pathways, PI3K, AKT and mTOR...

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Detalles Bibliográficos
Autores principales: Zhu, Kunrui, Wu, Yanqi, He, Ping, Fan, Yu, Zhong, Xiaorong, Zheng, Hong, Luo, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406657/
https://www.ncbi.nlm.nih.gov/pubmed/36010585
http://dx.doi.org/10.3390/cells11162508