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Development of Novel Therapeutics for Schizophrenia Treatment Based on a Selective Positive Allosteric Modulation of α1-Containing GABAARs—In Silico Approach

For the development of atypical antipsychotics, the selective positive allosteric modulation of the ionotropic GABAA receptor (GABAAR) has emerged as a promising approach. In the presented research, two unrelated methods were used for the development of QSAR models for selective positive allosteric...

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Detalles Bibliográficos
Autores principales: Đorđević, Vladimir, Petković, Milan, Živković, Jelena, Nikolić, Goran M., Veselinović, Aleksandar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406691/
https://www.ncbi.nlm.nih.gov/pubmed/36005130
http://dx.doi.org/10.3390/cimb44080234