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Oxygen Consumption and Basal Metabolic Rate as Markers of Susceptibility to Malignant Hyperthermia and Heat Stroke

Calsequestrin 1 (CASQ1) and Ryanodine receptor 1 (RYR1) are two of the main players in excitation–contraction (EC) coupling. CASQ1-knockout mice and mice carrying a mutation in RYR1 (Y522S) linked to human malignant hyperthermia susceptibility (MHS) both suffer lethal hypermetabolic episodes when ex...

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Detalles Bibliográficos
Autores principales: Serano, Matteo, Pietrangelo, Laura, Paolini, Cecilia, Guarnier, Flavia A., Protasi, Feliciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406760/
https://www.ncbi.nlm.nih.gov/pubmed/36010545
http://dx.doi.org/10.3390/cells11162468