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Integrated Excitatory/Inhibitory Imbalance and Transcriptomic Analysis Reveals the Association between Dysregulated Synaptic Genes and Anesthetic-Induced Cognitive Dysfunction

Emerging evidence from human epidemiologic and animal studies has demonstrated that developmental anesthesia neurotoxicity could cause long-term cognitive deficits and behavioral problems. However, the underlying mechanisms remain largely unknown. We conducted an electrophysiological analysis of syn...

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Detalles Bibliográficos
Autores principales: Yan, Yasheng, Logan, Sarah, Liu, Xiaojie, Chen, Bixuan, Jiang, Congshan, Arzua, Thiago, Ramchandran, Ramani, Liu, Qing-song, Bai, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406780/
https://www.ncbi.nlm.nih.gov/pubmed/36010580
http://dx.doi.org/10.3390/cells11162497