Cargando…

GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth

Hypoxia-inducible factor (HIF) directly activates the transcription of metabolic enzymes in response to hypoxia to reprogram cellular metabolism required for tumor cell proliferation. Through analyzing glutamate-linked aminotransferases, we here identified glutamate pyruvate transaminase 2 (GPT2) as...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Bo, Chen, Yan, Bao, Lei, Luo, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406858/
https://www.ncbi.nlm.nih.gov/pubmed/36010673
http://dx.doi.org/10.3390/cells11162597