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Palbociclib Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells via RB-Independent STAT3 Phosphorylation

Lung squamous cell carcinoma (LUSC) treatment response is poor and treatment alternatives are limited. Palbociclib, a cyclin-dependent kinase (CDK) 4/6 inhibitor, has recently been approved for hormone receptor-positive breast cancer patients and applied in multiple preclinical models, but its use f...

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Detalles Bibliográficos
Autores principales: Xiang, Wenjing, Qi, Wanchen, Li, Huayu, Sun, Jia, Dong, Chao, Ou, Haojie, Liu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406926/
https://www.ncbi.nlm.nih.gov/pubmed/36005200
http://dx.doi.org/10.3390/curroncol29080462