Increasing the Hydrophobic Component of Poloxamers and the Inclusion of Salt Extend the Release of Bupivacaine from Injectable In Situ Gels, While Common Polymer Additives Have Little Effect

Various strategies have been applied to reduce the initial burst of drug release and sustain release from poloxamer-based thermoresponsive gels. This work focussed on investigating different formulation approaches to minimise the initial burst of release and sustain the release of the small hydrophi...

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Detalles Bibliográficos
Autores principales: Abdeltawab, Hani, Svirskis, Darren, Hill, Andrew G., Sharma, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407117/
https://www.ncbi.nlm.nih.gov/pubmed/36005085
http://dx.doi.org/10.3390/gels8080484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407117/
https://www.ncbi.nlm.nih.gov/pubmed/36005085
http://dx.doi.org/10.3390/gels8080484

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