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Small molecule photocatalysis enables drug target identification via energy transfer

Over half of new therapeutic approaches fail in clinical trials due to a lack of target validation. As such, the development of new methods to improve and accelerate the identification of cellular targets, broadly known as target ID, remains a fundamental goal in drug discovery. While advances in se...

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Detalles Bibliográficos
Autores principales: Trowbridge, Aaron D., Seath, Ciaran P., Rodriguez-Rivera, Frances P., Li, Beryl X., Dul, Barbara E., Schwaid, Adam G., Buksh, Benito F., Geri, Jacob B., Oakley, James V., Fadeyi, Olugbeminiyi O., Oslund, Rob C., Ryu, Keun Ah, White, Cory, Reyes-Robles, Tamara, Tawa, Paul, Parker, Dann L., MacMillan, David W. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407219/
https://www.ncbi.nlm.nih.gov/pubmed/35969791
http://dx.doi.org/10.1073/pnas.2208077119