Examining the Diagnostic Yield of Tumour Testing and Qualifying Germline Concordance for Hereditary Cancer Variants in Patients with High-Grade Serous Carcinoma

Despite advances in treatment, prognosis for most patients with high-grade serous carcinoma (HGSC) remains poor. Genomic alterations in the homologous recombination (HR) pathway are used for cancer risk assessment and render tumours sensitive to platinum-based chemotherapy and poly (ADP-ribose) poly...

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Detalles Bibliográficos
Autores principales: Goebel, Emily A., Kerkhof, Jennifer, Dzyubak, Oleksandra, McLachlin, C. Meg, McGee, Jacob, Sadikovic, Bekim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407448/
https://www.ncbi.nlm.nih.gov/pubmed/36011309
http://dx.doi.org/10.3390/genes13081398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407448/
https://www.ncbi.nlm.nih.gov/pubmed/36011309
http://dx.doi.org/10.3390/genes13081398

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