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Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1

Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including Purkinje cells (PCs) in the cerebellum. Previous studies have demonstrated a critical role for various evolutionar...

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Detalles Bibliográficos
Autores principales: Luttik, Kimberly, Tejwani, Leon, Ju, Hyoungseok, Driessen, Terri, Smeets, Cleo J. L. M., Edamakanti, Chandrakanth Reddy, Khan, Aryaan, Yun, Joy, Opal, Puneet, Lim, Janghoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407543/
https://www.ncbi.nlm.nih.gov/pubmed/35969780
http://dx.doi.org/10.1073/pnas.2208513119