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The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the T(H)17 lineage in humans

Although glioblastoma multiforme (GBM) is not an invariably cold tumor, checkpoint inhibition has largely failed in GBM. In order to investigate T cell–intrinsic properties that contribute to the resistance of GBM to endogenous or therapeutically enhanced adaptive immune responses, we sorted CD4(+)...

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Detalles Bibliográficos
Autores principales: Mitsdoerffer, Meike, Aly, Lilian, Barz, Melanie, Engleitner, Thomas, Sie, Christopher, Delbridge, Claire, Lepennetier, Gildas, Öllinger, Rupert, Pfaller, Monika, Wiestler, Benedikt, Rad, Roland, Meyer, Bernhard, Knier, Benjamin, Schmidt-Graf, Friederike, Gempt, Jens, Korn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407554/
https://www.ncbi.nlm.nih.gov/pubmed/35969754
http://dx.doi.org/10.1073/pnas.2206208119