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The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the T(H)17 lineage in humans
Although glioblastoma multiforme (GBM) is not an invariably cold tumor, checkpoint inhibition has largely failed in GBM. In order to investigate T cell–intrinsic properties that contribute to the resistance of GBM to endogenous or therapeutically enhanced adaptive immune responses, we sorted CD4(+)...
Autores principales: | Mitsdoerffer, Meike, Aly, Lilian, Barz, Melanie, Engleitner, Thomas, Sie, Christopher, Delbridge, Claire, Lepennetier, Gildas, Öllinger, Rupert, Pfaller, Monika, Wiestler, Benedikt, Rad, Roland, Meyer, Bernhard, Knier, Benjamin, Schmidt-Graf, Friederike, Gempt, Jens, Korn, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407554/ https://www.ncbi.nlm.nih.gov/pubmed/35969754 http://dx.doi.org/10.1073/pnas.2206208119 |
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