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miR-23b-3p Modulating Cytoprotective Autophagy and Glutamine Addiction in Sorafenib Resistant HepG2, a Hepatocellular Carcinoma Cell Line

Background: Hepatocellular carcinoma (HCC) is the second most common malignancy with increasing cancer deaths worldwide. HCC is mainly diagnosed at its advanced stage, and treatment with FDA-approved sorafenib, the multikinase inhibitor drug, is advised. Acquired resistance against sorafenib develop...

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Detalles Bibliográficos
Autores principales: Kaur, Ramanpreet, Kanthaje, Shruthi, Taneja, Sunil, Dhiman, Radha K., Chakraborti, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407556/
https://www.ncbi.nlm.nih.gov/pubmed/36011286
http://dx.doi.org/10.3390/genes13081375