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DYF-5/MAK–dependent phosphorylation promotes ciliary tubulin unloading

Cilia are microtubule-based organelles that power cell motility and regulate sensation and signaling, and abnormal ciliary structure and function cause various ciliopathies. Cilium formation and maintenance requires intraflagellar transport (IFT), during which the kinesin-2 family motor proteins fer...

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Detalles Bibliográficos
Autores principales: Jiang, Xuguang, Shao, Wenxin, Chai, Yongping, Huang, Jingying, Mohamed, Mohamed A. A., Ökten, Zeynep, Li, Wei, Zhu, Zhiwen, Ou, Guangshuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407615/
https://www.ncbi.nlm.nih.gov/pubmed/35969738
http://dx.doi.org/10.1073/pnas.2207134119