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Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model

Sepsis, defined as organ dysfunction caused by a dysregulated host-response to infection, is characterized by immunosuppression. The vasopressor norepinephrine is widely used to treat low blood pressure in sepsis but exacerbates immunosuppression. An alternative vasopressor is angiotensin-II, a pept...

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Detalles Bibliográficos
Autores principales: Leisman, Daniel E., Privratsky, Jamie R., Lehman, Jake R., Abraham, Mabel N., Yaipan, Omar Y., Brewer, Mariana R., Nedeljkovic-Kurepa, Ana, Capone, Christine C., Fernandes, Tiago D., Griffiths, Robert, Stein, William J., Goldberg, Marcia B., Crowley, Steven D., Bellomo, Rinaldo, Deutschman, Clifford S., Taylor, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407661/
https://www.ncbi.nlm.nih.gov/pubmed/35969740
http://dx.doi.org/10.1073/pnas.2211370119