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Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model
Sepsis, defined as organ dysfunction caused by a dysregulated host-response to infection, is characterized by immunosuppression. The vasopressor norepinephrine is widely used to treat low blood pressure in sepsis but exacerbates immunosuppression. An alternative vasopressor is angiotensin-II, a pept...
Autores principales: | Leisman, Daniel E., Privratsky, Jamie R., Lehman, Jake R., Abraham, Mabel N., Yaipan, Omar Y., Brewer, Mariana R., Nedeljkovic-Kurepa, Ana, Capone, Christine C., Fernandes, Tiago D., Griffiths, Robert, Stein, William J., Goldberg, Marcia B., Crowley, Steven D., Bellomo, Rinaldo, Deutschman, Clifford S., Taylor, Matthew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407661/ https://www.ncbi.nlm.nih.gov/pubmed/35969740 http://dx.doi.org/10.1073/pnas.2211370119 |
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