Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability

Preserving a high degree of genome integrity and stability in germ cells is of utmost importance for reproduction and species propagation. However, the regulatory mechanisms of maintaining genome stability in the developing primordial germ cells (PGCs), in which rapid proliferation is coupled with g...

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Detalles Bibliográficos
Autores principales: Yang, Yajuan, Xu, Weiwei, Gao, Fei, Wen, Canxin, Zhao, Simin, Yu, Yongze, Jiao, Wenlin, Mi, Xin, Qin, Yingying, Chen, Zi-Jiang, Zhao, Shidou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407672/
https://www.ncbi.nlm.nih.gov/pubmed/35969748
http://dx.doi.org/10.1073/pnas.2203208119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407672/
https://www.ncbi.nlm.nih.gov/pubmed/35969748
http://dx.doi.org/10.1073/pnas.2203208119

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