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Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability
Preserving a high degree of genome integrity and stability in germ cells is of utmost importance for reproduction and species propagation. However, the regulatory mechanisms of maintaining genome stability in the developing primordial germ cells (PGCs), in which rapid proliferation is coupled with g...
Autores principales: | Yang, Yajuan, Xu, Weiwei, Gao, Fei, Wen, Canxin, Zhao, Simin, Yu, Yongze, Jiao, Wenlin, Mi, Xin, Qin, Yingying, Chen, Zi-Jiang, Zhao, Shidou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407672/ https://www.ncbi.nlm.nih.gov/pubmed/35969748 http://dx.doi.org/10.1073/pnas.2203208119 |
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