Cargando…

Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status

Dynamic regulation of mitochondrial morphology provides cells with the flexibility required to adapt and respond to electron transport chain (ETC) toxins and mitochondrial DNA-linked disease mutations, yet the mechanisms underpinning the regulation of mitochondrial dynamics machinery by these stimul...

Descripción completa

Detalles Bibliográficos
Autores principales: Thoudam, Themis, Chanda, Dipanjan, Sinam, Ibotombi Singh, Kim, Byung-Gyu, Kim, Mi-Jin, Oh, Chang Joo, Lee, Jung Yi, Kim, Min-Ji, Park, Soo Yeun, Lee, Shin Yup, Jung, Min-Kyo, Mun, Ji Young, Harris, Robert A., Ishihara, Naotada, Jeon, Jae-Han, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407676/
https://www.ncbi.nlm.nih.gov/pubmed/35969774
http://dx.doi.org/10.1073/pnas.2120157119