Cargando…

Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status

Dynamic regulation of mitochondrial morphology provides cells with the flexibility required to adapt and respond to electron transport chain (ETC) toxins and mitochondrial DNA-linked disease mutations, yet the mechanisms underpinning the regulation of mitochondrial dynamics machinery by these stimul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thoudam, Themis, Chanda, Dipanjan, Sinam, Ibotombi Singh, Kim, Byung-Gyu, Kim, Mi-Jin, Oh, Chang Joo, Lee, Jung Yi, Kim, Min-Ji, Park, Soo Yeun, Lee, Shin Yup, Jung, Min-Kyo, Mun, Ji Young, Harris, Robert A., Ishihara, Naotada, Jeon, Jae-Han, Lee, In-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407676/ https://www.ncbi.nlm.nih.gov/pubmed/35969774 http://dx.doi.org/10.1073/pnas.2120157119

Ejemplares similares

Pyruvate dehydrogenase kinase 4 promotes ubiquitin–proteasome system‐dependent muscle atrophy
por: Sinam, Ibotombi Singh, et al.
Publicado: (2022)

Enhanced Ca(2+)-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease
por: Thoudam, Themis, et al.
Publicado: (2023)

The Role of Pyruvate Metabolism in Mitochondrial Quality Control and Inflammation
por: Kim, Min-Ji, et al.
Publicado: (2023)

The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4
por: Kim, Min-Ji, et al.
Publicado: (2023)

PDK4 Augments ER–Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity
por: Thoudam, Themis, et al.
Publicado: (2019)

Upregulation of the ERRγ–VDAC1 axis underlies the molecular pathogenesis of pancreatitis
por: Chanda, Dipanjan, et al.
Publicado: (2023)

SAT004 A Novel Therapeutic Target Of Mitochondrial Protein To Prevent Steroid-induced Muscle Atrophy Through Regulation Of Proteolysis And Myogenesis
por: Kim, Min-Ji, et al.
Publicado: (2023)

Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases
por: Jeon, Jae‐Han, et al.
Publicado: (2020)

Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4(+) T Cells Ameliorates Intestinal Inflammation
por: Lee, Hoyul, et al.
Publicado: (2022)

Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRγ
por: Lee, Ja Hee, et al.
Publicado: (2012)

Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases
por: Thoudam, Themis, et al.
Publicado: (2016)

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism
por: Park, Sungmi, et al.
Publicado: (2018)

Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway
por: Kim, Hyebeen, et al.
Publicado: (2020)

PDK1 is a negative regulator of axon regeneration
por: Kim, Hyemin, et al.
Publicado: (2021)

Astrocyte glucose metabolism highlights the link between cannabis use and social behavior
por: Chanda, Dipanjan, et al.
Publicado: (2021)

Prediction of hearing outcomes in chronic otitis media patients underwent tympanoplasty using ossiculoplasty outcome parameter staging or middle ear risk indices
por: Jung, Da Jung, et al.
Publicado: (2021)

Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme
por: Han, Jiwon Esther, et al.
Publicado: (2017)

Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
por: Min, Kyungjin, et al.
Publicado: (2020)

Construction and Application of Elastin Like Polypeptide Containing IL-4 Receptor Targeting Peptide
por: Sarangthem, Vijaya, et al.
Publicado: (2013)

ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65
por: Kim, Min-Young, et al.
Publicado: (2015)

The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells
por: Han, Ji-Youn, et al.
Publicado: (1999)

Editorial: The role of oxidative stress and systemic inflammation in diabetes and chronic kidney disease
por: Chanda, Dipanjan, et al.
Publicado: (2023)

PKCθ-Mediated PDK1 Phosphorylation Enhances T Cell Activation by Increasing PDK1 Stability
por: Kang, Jung-Ah, et al.
Publicado: (2017)

Necrotizing Fasciitis in Three University Hospitals in Korea: A Change in Causative Microorganisms and Risk Factors of Mortality During the Last Decade
por: Yu, Shi Nae, et al.
Publicado: (2013)

The Kinase PDK1 Is Essential for B-Cell Receptor Mediated Survival Signaling
por: Park, Sung-Gyoo, et al.
Publicado: (2013)

Ultrastructural Changes in Skeletal Muscle of Infants with Mitochondrial Respiratory Chain Complex I Defects
por: Mun, Ji Young, et al.
Publicado: (2017)

Metformin Inhibits Growth Hormone–Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner
por: Kim, Yong Deuk, et al.
Publicado: (2012)

Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels
por: Nam, Seo Hee, et al.
Publicado: (2015)

Erratum: Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels
por: Nam, Seo Hee, et al.
Publicado: (2016)

Multipurpose assessment for the quantification of Vibrio spp. and total bacteria in fish and seawater using multiplex real-time polymerase chain reaction
por: Kim, Ji Yeun, et al.
Publicado: (2014)

Inhibitory Effects of Hwangryunhaedok-Tang in 3T3-L1 Adipogenesis by Regulation of Raf/MEK1/ERK1/2 Pathway and PDK1/Akt Phosphorylation
por: Kwak, Dong Hoon, et al.
Publicado: (2013)

Striatal Dopaminergic Loss and Dysphagia in Parkinson Disease
por: Kim, Ji Hwan, et al.
Publicado: (2023)

Co-existence of relapsing polychondritis and Crohn disease treated successfully with infliximab
por: Jung, Hye-In, et al.
Publicado: (2020)

Spontaneous migration of a congenital intratympanic membrane cholesteatoma
por: Kim, Tae Hoon, et al.
Publicado: (2018)

One-year Results of Aflibercept Treatment for Polypoidal Choroidal Vasculopathy with Good Visual Acuity
por: Kwon, Ji Min, et al.
Publicado: (2021)

Clinical Usefulness of Aripiprazole and Lamotrigine in Schizoaffective Presentation of Tuberous Sclerosis
por: Lee, Seung-Yup, et al.
Publicado: (2016)

Mitochondrial nucleoid trafficking regulated by the inner-membrane AAA-ATPase ATAD3A modulates respiratory complex formation
por: Ishihara, Takaya, et al.
Publicado: (2022)

Diagnostic value of the molecular detection of Sarcoptes scabiei from a skin scraping in patients with suspected scabies
por: Bae, Moonsuk, et al.
Publicado: (2020)

Uracil-DNA glycosylase-treated reverse transcription loop-mediated isothermal amplification for rapid detection of avian influenza virus preventing carry-over contamination
por: Kim, Eun-Mi, et al.
Publicado: (2016)

Retinol, α-tocopherol, and selected minerals in breast milk of lactating women with full-term infants in South Korea
por: Kim, Hyesook, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_uq62tv48f087v47din4rbesmsn