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An Antibody from Single Human V(H)-rearranging Mouse Neutralizes All SARS-CoV-2 Variants Through BA.5 by Inhibiting Membrane Fusion

SARS-CoV-2 Omicron sub-variants have generated a world-wide health crisis due to resistance to most approved SARS-CoV-2 neutralizing antibodies and evasion of vaccination-induced antibodies. To manage Omicron sub-variants and prepare for potential new variants, additional means of isolating broad an...

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Detalles Bibliográficos
Autores principales: Luo, Sai, Zhang, Jun, Kreutzberger, Alex J.B., Eaton, Amanda, Edwards, Robert J., Jing, Changbin, Dai, Hai-Qiang, Sempowski, Gregory D., Cronin, Kenneth, Parks, Robert, Ye, Adam Yongxin, Mansouri, Katayoun, Barr, Maggie, Pishesha, Novalia, Williams, Aimee Chapdelaine, Vieira Francisco, Lucas, Saminathan, Anand, Peng, Hanqin, Batra, Himanshu, Bellusci, Lorenza, Khurana, Surender, Alam, S. Munir, Montefiori, David C., Saunders, Kevin O., Tian, Ming, Ploegh, Hidde, Kirchhausen, Tom, Chen, Bing, Haynes, Barton F., Alt, Frederick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407951/
https://www.ncbi.nlm.nih.gov/pubmed/35951767
http://dx.doi.org/10.1126/sciimmunol.add5446