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Acetylation-Specific Interference by Anti-Histone H3K9ac Intrabody Results in Precise Modulation of Gene Expression

Among Histone post-translational modifications (PTMs), lysine acetylation plays a pivotal role in the epigenetic regulation of gene expression, mediated by chromatin modifying enzymes. Due to their activity in physiology and pathology, several chemical compounds have been developed to inhibit the fu...

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Detalles Bibliográficos
Autores principales: Lisi, Simonetta, Trovato, Matteo, Vitaloni, Ottavia, Fantini, Marco, Chirichella, Michele, Tognini, Paola, Cornuti, Sara, Costa, Mario, Groth, Marco, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408029/
https://www.ncbi.nlm.nih.gov/pubmed/36012156
http://dx.doi.org/10.3390/ijms23168892