Complexing the Oncolytic Adenoviruses Ad∆∆ and Ad-3∆-A20T with Cationic Nanoparticles Enhances Viral Infection and Spread in Prostate and Pancreatic Cancer Models

Oncolytic adenoviruses (OAd) can be employed to efficiently eliminate cancer cells through multiple mechanisms of action including cell lysis and immune activation. Our OAds, AdΔΔ and Ad-3∆-A20T, selectively infect, replicate in, and kill adenocarcinoma cells with the added benefit of re-sensitising...

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Detalles Bibliográficos
Autores principales: Man, Yang Kee Stella, Aguirre-Hernandez, Carmen, Fernandez, Adrian, Martin-Duque, Pilar, González-Pastor, Rebeca, Halldén, Gunnel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408166/
https://www.ncbi.nlm.nih.gov/pubmed/36012152
http://dx.doi.org/10.3390/ijms23168884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408166/
https://www.ncbi.nlm.nih.gov/pubmed/36012152
http://dx.doi.org/10.3390/ijms23168884

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