Structural Insights and Development of LRRK2 Inhibitors for Parkinson’s Disease in the Last Decade

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease, characterized by the specific loss of dopaminergic neurons in the midbrain. The pathophysiology of PD is likely caused by a variety of environmental and hereditary factors. Many single-gene mutations have been linked to...

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Detalles Bibliográficos
Autores principales: Thakur, Gunjan, Kumar, Vikas, Lee, Keun Woo, Won, Chungkil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408223/
https://www.ncbi.nlm.nih.gov/pubmed/36011337
http://dx.doi.org/10.3390/genes13081426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408223/
https://www.ncbi.nlm.nih.gov/pubmed/36011337
http://dx.doi.org/10.3390/genes13081426

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