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Structural Insights and Development of LRRK2 Inhibitors for Parkinson’s Disease in the Last Decade
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease, characterized by the specific loss of dopaminergic neurons in the midbrain. The pathophysiology of PD is likely caused by a variety of environmental and hereditary factors. Many single-gene mutations have been linked to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408223/ https://www.ncbi.nlm.nih.gov/pubmed/36011337 http://dx.doi.org/10.3390/genes13081426 |