MiR-18a-5p Targets Connective Tissue Growth Factor Expression and Inhibits Transforming Growth Factor β2-Induced Trabecular Meshwork Cell Contractility

Increased trabecular meshwork (TM) cell and tissue contractility is a driver of the reduced outflow facility and elevation of intraocular pressure (IOP) associated with primary open-angle glaucoma (POAG). Connective tissue growth factor (CTGF) is an established mediator of TM cell contractility, and...

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Detalles Bibliográficos
Autores principales: Knox, John, Bou-Gharios, George, Hamill, Kevin J., Willoughby, Colin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408287/
https://www.ncbi.nlm.nih.gov/pubmed/36011411
http://dx.doi.org/10.3390/genes13081500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408287/
https://www.ncbi.nlm.nih.gov/pubmed/36011411
http://dx.doi.org/10.3390/genes13081500

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