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CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain

The IQ motif-containing GTPase-activating protein (IQGAP) family composes of three highly-related and evolutionarily conserved paralogs (IQGAP1, IQGAP2 and IQGAP3), which fine tune as scaffolding proteins numerous fundamental cellular processes. IQGAP1 is described as an effector of CDC42, although...

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Detalles Bibliográficos
Autores principales: Mosaddeghzadeh, Niloufar, Pudewell, Silke, Bazgir, Farhad, Kazemein Jasemi, Neda S., Krumbach, Oliver H. F., Gremer, Lothar, Willbold, Dieter, Dvorsky, Radovan, Ahmadian, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408373/
https://www.ncbi.nlm.nih.gov/pubmed/36012107
http://dx.doi.org/10.3390/ijms23168842