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LHX2 Enhances the Malignant Phenotype of Esophageal Squamous Cell Carcinoma by Upregulating the Expression of SERPINE2

LHX2 dysregulations have been found to present in cancers, but the function of LHX2 in esophageal squamous cell carcinoma (ESCC) remains unknown. Here, we report that LHX2 was upregulated in ESCC tissues in comparison to the LHX2 levels in adjacent normal tissues. Loss- and gain-of-function experime...

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Detalles Bibliográficos
Autores principales: Li, Xukun, Wu, Xueling, Chen, Hongyan, Liu, Zhihua, He, Huan, Wang, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408536/
https://www.ncbi.nlm.nih.gov/pubmed/36011368
http://dx.doi.org/10.3390/genes13081457