Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen

We examined proteomic profiles of rat liver extracellular vesicles (EVs) shed following treatment with a sub-toxic dose (500 mg/kg) of the pain reliever drug, acetaminophen (APAP). EVs representing the entire complement of hepatic cells were isolated after perfusion of the intact liver and analyzed...

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Detalles Bibliográficos
Autores principales: Šrajer Gajdošik, Martina, Kovač Peić, Anamarija, Begić, Marija, Grbčić, Petra, Brilliant, Kate E., Hixson, Douglas C., Josić, Djuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408656/
https://www.ncbi.nlm.nih.gov/pubmed/36012131
http://dx.doi.org/10.3390/ijms23168870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408656/
https://www.ncbi.nlm.nih.gov/pubmed/36012131
http://dx.doi.org/10.3390/ijms23168870

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