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Size and Methylation Index of Cell-Free and Cell-Surface-Bound DNA in Blood of Breast Cancer Patients in the Contest of Liquid Biopsy

Aberrantly methylated circulating DNA (cirDNA) has proven to be a good cancer marker, but its detection is limited by low concentrations, fragmentation, and insufficiency. Since the methylated cirDNA was shown to be more stable in circulation than the unmethylated one and was shown to bind with the...

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Detalles Bibliográficos
Autores principales: Tamkovich, Svetlana, Tupikin, Alexey, Kozyakov, Anton, Laktionov, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408721/
https://www.ncbi.nlm.nih.gov/pubmed/36012175
http://dx.doi.org/10.3390/ijms23168919