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Externalization of Mitochondrial PDCE2 on Irradiated Endothelium as a Target for Radiation-Guided Drug Delivery and Precision Thrombosis of Pathological Vasculature

Endothelial cells are highly sensitive to ionizing radiation, and exposure leads to multiple adaptive changes. Remarkably, part of this response is the translocation of normally intracellular proteins to the cell surface. It is unclear whether this ectopic expression has a protective or deleterious...

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Detalles Bibliográficos
Autores principales: Faqihi, Fahimeh, Stoodley, Marcus A., McRobb, Lucinda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408815/
https://www.ncbi.nlm.nih.gov/pubmed/36012169
http://dx.doi.org/10.3390/ijms23168908