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Effective Perturbations by Small-Molecule Modulators on Voltage-Dependent Hysteresis of Transmembrane Ionic Currents

The non-linear voltage-dependent hysteresis (Hys((V))) of voltage-gated ionic currents can be robustly activated by the isosceles-triangular ramp voltage (V(ramp)) through digital-to-analog conversion. Perturbations on this Hys((V)) behavior play a role in regulating membrane excitability in differe...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Nan, Wu, Chao-Liang, Cho, Hsin-Yen, Chiang, Chi-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408818/
https://www.ncbi.nlm.nih.gov/pubmed/36012718
http://dx.doi.org/10.3390/ijms23169453