Cargando…

FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer’s Disease

The non-receptor focal adhesion kinase (FAK) is highly expressed in the central nervous system during development, where it regulates neurite outgrowth and axon guidance, but its role in the adult healthy and diseased brain, specifically in Alzheimer’s disease (AD), is largely unknown. Using the 3xT...

Descripción completa

Detalles Bibliográficos
Autores principales: Saleh, Bisan, Srikanth, Kolluru D., Sneh, Tal, Yue, Lambert, Pelech, Steven, Elliott, Evan, Gil-Henn, Hava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408823/
https://www.ncbi.nlm.nih.gov/pubmed/36012331
http://dx.doi.org/10.3390/ijms23169055