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FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer’s Disease
The non-receptor focal adhesion kinase (FAK) is highly expressed in the central nervous system during development, where it regulates neurite outgrowth and axon guidance, but its role in the adult healthy and diseased brain, specifically in Alzheimer’s disease (AD), is largely unknown. Using the 3xT...
Autores principales: | Saleh, Bisan, Srikanth, Kolluru D., Sneh, Tal, Yue, Lambert, Pelech, Steven, Elliott, Evan, Gil-Henn, Hava |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408823/ https://www.ncbi.nlm.nih.gov/pubmed/36012331 http://dx.doi.org/10.3390/ijms23169055 |
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