Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities

Cartilage oligomeric matrix protein (COMP) is an extracellular matrix (ECM) glycoprotein that is critical for collagen assembly and ECM stability. Mutations of COMP cause endoplasmic reticulum stress and chondrocyte apoptosis, resulting in rare skeleton diseases. The bouquet-like structure of COMP a...

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Detalles Bibliográficos
Autores principales: Cui, Jiarui, Zhang, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408827/
https://www.ncbi.nlm.nih.gov/pubmed/36012514
http://dx.doi.org/10.3390/ijms23169253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408827/
https://www.ncbi.nlm.nih.gov/pubmed/36012514
http://dx.doi.org/10.3390/ijms23169253

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