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Nonsteroidal Mineralocorticoid Receptor Antagonism by Finerenone—Translational Aspects and Clinical Perspectives across Multiple Organ Systems

Perception of the role of the aldosterone/mineralocorticoid receptor (MR) ensemble has been extended from a previously renal epithelial-centered focus on sodium and volume homeostasis to an understanding of their role as systemic modulators of reactive oxygen species, inflammation, and fibrosis. Ste...

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Detalles Bibliográficos
Autores principales: Kolkhof, Peter, Lawatscheck, Robert, Filippatos, Gerasimos, Bakris, George L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408839/
https://www.ncbi.nlm.nih.gov/pubmed/36012508
http://dx.doi.org/10.3390/ijms23169243