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Cellular Electrical Impedance as a Method to Decipher CCR7 Signalling and Biased Agonism

The human C-C chemokine receptor type 7 (CCR7) has two endogenous ligands, C-C chemokine ligand 19 (CCL19) and CCL21, displaying biased agonism reflected by a pronounced difference in the level of β-arrestin recruitment. Detecting this preferential activation generally requires the use of separate,...

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Detalles Bibliográficos
Autores principales: Vanalken, Nathan, Boon, Katrijn, Doijen, Jordi, Schols, Dominique, Van Loy, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408853/
https://www.ncbi.nlm.nih.gov/pubmed/36012168
http://dx.doi.org/10.3390/ijms23168903