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Cellular Electrical Impedance as a Method to Decipher CCR7 Signalling and Biased Agonism
The human C-C chemokine receptor type 7 (CCR7) has two endogenous ligands, C-C chemokine ligand 19 (CCL19) and CCL21, displaying biased agonism reflected by a pronounced difference in the level of β-arrestin recruitment. Detecting this preferential activation generally requires the use of separate,...
Autores principales: | Vanalken, Nathan, Boon, Katrijn, Doijen, Jordi, Schols, Dominique, Van Loy, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408853/ https://www.ncbi.nlm.nih.gov/pubmed/36012168 http://dx.doi.org/10.3390/ijms23168903 |
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