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Cell-Type Dependent Regulation of the Electrogenic Na(+)/HCO(3)(−) Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma
Glioblastoma multiforme (GBM) is the most common and malignant brain tumour. It is characterised by transcriptionally distinct cell populations. In tumour cells, physiological pH gradients between the intracellular and extracellular compartments are reversed, compared to non-cancer cells. Intracellu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408864/ https://www.ncbi.nlm.nih.gov/pubmed/36012235 http://dx.doi.org/10.3390/ijms23168975 |