Cargando…

Cell-Type Dependent Regulation of the Electrogenic Na(+)/HCO(3)(−) Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma

Glioblastoma multiforme (GBM) is the most common and malignant brain tumour. It is characterised by transcriptionally distinct cell populations. In tumour cells, physiological pH gradients between the intracellular and extracellular compartments are reversed, compared to non-cancer cells. Intracellu...

Descripción completa

Detalles Bibliográficos
Autores principales: Giannaki, Marina, Ruf, Debora E., Pfeifer, Emilie, Everaerts, Katharina, Heiland, Dieter H., Schnell, Oliver, Rose, Christine R., Roussa, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408864/
https://www.ncbi.nlm.nih.gov/pubmed/36012235
http://dx.doi.org/10.3390/ijms23168975