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High IGKC-Expressing Intratumoral Plasma Cells Predict Response to Immune Checkpoint Blockade

Resistance to Immune Checkpoint Blockade (ICB) constitutes the current limiting factor for the optimal implementation of this novel therapy, which otherwise demonstrates durable responses with acceptable toxicity scores. This limitation is exacerbated by a lack of robust biomarkers. In this study, w...

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Detalles Bibliográficos
Autores principales: Onieva, Juan Luis, Xiao, Qingyang, Berciano-Guerrero, Miguel-Ángel, Laborda-Illanes, Aurora, de Andrea, Carlos, Chaves, Patricia, Piñeiro, Pilar, Garrido-Aranda, Alicia, Gallego, Elena, Sojo, Belén, Gálvez, Laura, Chica-Parrado, Rosario, Prieto, Daniel, Pérez-Ruiz, Elisabeth, Farngren, Angela, Lozano, María José, Álvarez, Martina, Jiménez, Pedro, Sánchez-Muñoz, Alfonso, Oliver, Javier, Cobo, Manuel, Alba, Emilio, Barragán, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408876/
https://www.ncbi.nlm.nih.gov/pubmed/36012390
http://dx.doi.org/10.3390/ijms23169124